Saturday, January 28, 2017

Sorafenib Sorafenat Tablets for Treatment of Chronic Cancer

Natco Sorafenib Tablets Specification: 
  • Brand Name : Sorafenat
  • Active Ingredients : Sorafenib Tosylate
  • Manufactured by: Natco Pharma Ltd.
  • Strength: 200 mg
  • Form: Tablets
  • Packing: Pack of 120 Tablets
The usage of Sorafenib Tablet Natco is primarily for targeted therapy during treatment of liver and kidney cancer. The commercial name of the drug is Nexavar. The drug is a Tyrosine Kinase and Angiogenesis inhibitor, along with working as an inhibitor for Vascular Endothelial Growth Factor (VEGF).

Targeted Therapy

Conventional cancer treatment focuses on killing the mutating and rapidly divisive cancer cells. While this mode of treatment was somewhat effective, the medication was harmful to the normal cells of the body also, causing a lot of undesired side effects. Targeted therapy in cancer treatment focuses on different areas; the differences between the cancerous cell and the healthy ones are identified. These characteristics are then used to attack specific cells without damaging the normal ones. While the processes may vary, the treatment works toward interfering with the growth, repairing mechanism, ability to multiply and communicate with other cells. Generic Sorafenib tablets are Anti-Angiogenesis drugs, which disrupt the supply of oxygen, causing starvation in the cell.

Types of Cancer Treatable by Nexavar Sorafenib Tablet:

While this drug is generally used for the treatment of cancers mentioned below, Oncologists might prescribe the medicine if they find it useful in other cancer types also.
  • Hepato Cellular Carcinoma (HCC)
  • Thyroid cancer
  • Renal Cancer
Dosage

The drug is administered by mouth, preferably before taking food. A gap of 1 to 2 hours is recommended before or after food intake for the effectiveness of the drug. The commercial availability of the drug is in Soranib 200 mg tablet form, though the amounts prescribed vary for patients as per doctor's discretion.

Side Effects

As with any current cancer medicine, the side effects are an inevitable part of the usage of Nexavar Sorafenib Tablets. The following common side effects may occur in patients.
  • Rash
  • Fatigue
  • Diarrhea
  • Increase in Blood Pressure
  • Hair Loss
  • Vomiting
  • Bleeding
  • Muscle or joint pain


While almost all symptoms are reversible and disappear after discontinuation of medication, consult your oncologist any of them persist or cause major discomfort. An adjustment of the dosage might be required after few weeks. Keep special note of a rarer but serious side effect of Soranib 200 mg which affects the heart and may cause a heart attack.

Some Precautions

While your doctor will give detailed instructions, the following general precautions may be followed.
  • Inform your doctor about all ongoing medications
  • Don't undergo any immunization procedures
  • Inform about pregnancy or its planning
  • Do not breast-feed

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